NewsFrom: David Page Date: Mon, 1 Oct 2001 17:15:54 -0500 (CDT) Subject: KDD Cup 2001 results and summary Because of the importance and rapid growth of biological data, KDD Cup 2001 focused on mining biological databases. The competition featured three tasks, based on two databases. The first task required accurate prediction of molecules that bind to Thrombin. Each molecule was described by a record of nearly 140,000 Boolean features. The database was graciously provided by DuPont Pharmaceuticals Research Laboratories. This task is representative of a large domain of tasks from the field of drug design. In each such task, an accurate and comprehensible predictor of activity often can be used to guide the design of new drugs. The second and third tasks centered on a database with properties of the Yeast genome and proteome. For each gene, the database gave the chromosome on which the gene appears and properties of organisms with mutations in this gene, including viability. For each gene, the database also described properties of the protein for which it codes, including its structural class and complex, as well as other proteins with which it interacts. Also included were correlations in gene expression, as measured by gene expression microarrays. Finally, for the "training" genes only, the database recorded protein functions and localization (where in the cell the protein typically is located). The second and third tasks were to predict function and localization, respectively. The winner of Task 1 was Jie Cheng, of the Canadian Imperial Bank of Commerce. The winner of Task 2 was Mark-A. Krogel of the University of Magdeburg. The winner of Task 3 was the team of Hisashi Hayashi, Jun Sese, and Shinichi Morishita of the University of Tokyo. Details of the winners' approaches are available in their KDD presentations, online at the KDD Cup 2001 web site: www.cs.wisc.edu/~dpage/kddcup2001 Participation was outstanding, with 136 groups submitting a total of 200 predictions for the three tasks. Further details on participation and techniques employed also are available at the web site. |
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